Results 121 to 130 of about 282,171 (310)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Prethermalization in coupled one-dimensional quantum gases
SciPost PhysicsWe consider the problem of the development of steady states in one-dimensional Bose gas tubes that are weakly coupled to one another through a density-density interaction. We analyze this development through a Boltzmann collision integral approach.
Maciej Łebek, Miłosz Panfil, Robert M. Konik
doaj +1 more source
Intuitive interaction: Steps towards an integral understanding of the user experience in interaction design [PDF]
A critical review of traditional practices and methodologies demonstrates an underplaying of firstly the role of emotions and secondly aspects of exploration in interaction behaviour in favour of a goal orientated focus in the user experience (UX ...
Kaltenbacher, Brigitte
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Studying direct-touch interaction for 2D flow visualization
, 2015 Traditionally, scientific visualization research concentrates on the development and improvement of interactive techniques to support expert data analysis.
Hinrichs, Uta +2 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Capacities and Games on Lattices: A Survey of Result [PDF]
We provide a survey of recent developments about capacities (or fuzzy measures) and ccoperative games in characteristic form, when they are defined on more general structures than the usual power set of the universal set, namely lattices. In a first part,
Michel Grabisch
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
CRITICAL TEMPERATURE OF THE SUPERFLUIDTRANSITION IN FERMI-SYSTEM AT AN ARBITRARY PAIR POTENTIAL
East European Journal of Physics, 2015 A method for calculation of the critical temperature of transition of a many-particle Fermi system into a superfluid or a superconducting state at an arbitrary pair potential of the interparticle interaction is proposed.
Yu. M. Poluektov, A. A. Soroka
doaj