Results 131 to 140 of about 282,171 (310)
Integral bridges: modelling the soil-structure interaction
, 2012 Integral abutment bridges, also known as integral bridges, have become one of the most common types of joint-less bridge construction, certainly over the last three decades.
David, Thevaneyan Krishta David
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
VERTICES IN A SCALAR-GRAVITY SYSTEM IN THE TELEPARALLEL GRAVITY THEORY
, 2014 We consider a scalar field interacting gravitationally in teleparallel gravity theory. In this theory, the gravity is defined as a translational gauge field and thus gravita- tional interaction can be introduced through a minimal coupling prescription as
Ming, Kian, Triyanta, Triyanta
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
RUDN Journal of Political Science, 2008 We make an attempt in the article to make an integral consideration of business as a semi functional activity in interaction with society, the general methodological approaches are suggested to analyze it as a socio-political phenomenon.
A V Aleynikov
doaj
Bipolarization of posets and natural interpolation [PDF]
The Choquet integral w.r.t. a capacity can be seen in the finite case as a parsimonious linear interpolator between vertices of $[0,1]^n$. We take this basic fact as a starting point to define the Choquet integral in a very general way, using the ...
Michel Grabisch, Christophe Labreuche
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
DIALOG ILMU DAN IMAN: SUATU PENDEKATAN DAN CARA REALISASINYA
, 2014 Awareness of development in science and its underlying scientic method, and its widening influence on society, reminds one of another strong influence, which is religion and its underlying faith.
Rusli, Aloysius
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source