The Interactional Function of Japanese Interactive Markers yo and sa
Linguistics and the Human Sciences, 2012 This study investigates the interactional function of Japanese interactive markers yo and sa in conjunction with the notion of involvement, and sheds light on some issues of verbal exchange in spoken discourse. The study argues that these markers commonly share the function of signalling the speaker’s attitude of inviting the hearer’s involvement in a
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A Comparative Analysis of Metadiscourse Markers in the Result and Discussion Sections of Literature and Engineering Research Papers [PDF]
Iranian Journal of Applied Language Studies, 2017 This study compares metadiscourse markers in result and discussion sections of literature and engineering research papers. To this end, 40 research articles (20 literature and 20 engineering) are selected from two major international journals.
Maryam Kahkesh, Mohammad Alipour
doaj +1 more source
What does not happen: quantifying embodied engagement using NIMI and self-adaptors [PDF]
, 2014 Previous research into the quantification of embodied intellectual and emotional engagement using non-verbal movement parameters has not yielded consistent results across different studies.
Chockalingam, Nachiappan +5 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Discourse markers and interactional competence marcadores del discurso y competencia interaccional [PDF]
, 2016 Communicating with people from different countries implies not only choosing the appropriate words but also using appropriate verbal and non-verbal resources in order to enhance communicative effectiveness and thus be perceived as being interactionally ...
Gregori-Signes, Carmen +2 more
core +1 more source
‘What’s it like to have ME?’ The discursive construction of ME in computer-mediated communication and face-to-face interaction [PDF]
, 2007 ME/CFS (chronic fatigue syndrome) is a debilitating illness for which no cause or medical tests have been identified. Debates over its nature have generated interest from qualitative researchers.
Andy McKinlay +17 more
core +5 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A comparative analysis of interactional metadiscourse markers in the Introduction and Conclusion sections of mechanical and electrical engineering research papers [PDF]
Iranian Journal of Language Teaching Research, 2015 Academic writing, particularly writing research articles, is an indispensable part of every major in higher education. Hyland (2004) argued that a valuable means of exploring academic writing, and comparing the rhetorical features and preferences of ...
Masoomeh Estaji, Roya Vafaeimehr
doaj