Results 71 to 80 of about 943,395 (244)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An Investigation of Metadiscourse Features in International Postgraduate Business Students’ Texts
SAGE Open, 2015 Metadiscourse analysis reveals the way writers engage with different texts and communicate with each other. Examining these linguistic resources is important because they play a vital role in maximizing the learning experiences of students in the Master ...
Hesham Suleiman Alyousef
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A dynamic-interactional approach to discourse markers
, 2006 Frank-Job B. A dynamic-interactional approach to discourse markers. In: Fischer K, ed. Approaches to Discourse Particles. Studies in Pragmatics. Vol 1.
Fischer, Kerstin +1 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
MATEC Web of Conferences, 2018 There is lack of studies on the use of metadiscourse markers; especially amongst international students studying in Malaysia and Malaysia are receiving scores of international students particularly from the Middle East annually.
Khairul Zakaria Muhamad +1 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The Use of Interactional Metadiscourse Markers in the Results and Discussion Sections of Algerian Scientific Research Articles [PDF]
, 2020 30cm.; 95p.; tabl.+cdThe present study aims at exploring the use of Interactional Metadiscourse Markers in the Results and Discussion sections of twenty (20) Algerian Scientific Research Articles. Four objectives have motivated our research.
KADIR, Wissam
core
Journal of Applied Linguistics and LiteratureThis study presents a comparative corpus analysis of interactional metadiscourse features in two English textbooks used in Indonesian senior high schools: an EFL textbook published by the Indonesian Ministry of Education and Culture (Bahasa Inggris ...
Rismar Riansih +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source