Results 61 to 70 of about 3,381 (297)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Use Of Interactional Metadiscourse in Students' Essay [PDF]
, 2022 This study aims to analyze and find out the Interactional Metadiscourse that is frequently used in the students’ essay. This research was conducted to reveal Interactional Metadiscourse in Students’ Essay At English Department of UIN Antasari ...
Khalidah, Noor
core
The arts of lobbying: Scrutinizing the functions of interactional meta-discourse in Model United Nations conferences [PDF]
, 2023 This study explores how speakers use interactional markers in the diplomatic speech Model United Nations Conference. We used a discourse analysis approach focusing on the meta-discourse markers; the analyzed data comes from the speech utterances based on
Rizqy, Muhammad Hifni Sahila +1 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2023 Interactional metadiscourse has a very significant role in writing. Instead of merely providing information to the readers, interactional metadiscourse helps the writer to communicate their ideas in a way that readers are familiar with and they can ...
Ira, Maisarah +2 more
core
Disrupted network interactions serve as a neural marker of dyslexia
Communications Biology, 2023 AbstractDyslexia, a frequent learning disorder, is characterized by severe impairments in reading and writing and hypoactivation in reading regions in the left hemisphere. Despite decades of research, it remains unclear to date if observed behavioural deficits are caused by aberrant network interactions during reading and whether differences in ...
Sabrina Turker +3 more
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Imperceptible AR Markers for Near-Screen Mobile Interaction [PDF]
IEEE Access, 2019 Owing to the pervasive use of displays and smartphones, mobile interactions with display screens have gained attention within the advertising and gaming industries as well as in human-computer interaction research. Communication through QR code-like markers and localization via AR markers are common examples of such interactions. However, these visible
Akira Matsumoto +4 more
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Asian-Pacific Journal of Second and Foreign Language Education, 2022 The current study aimed to compare the influence of explicit versus implicit instruction on EFL learners’ use of interactional metadiscourse markers in their writing.
Dina Abdel Salam El-Dakhs +2 more
doaj +1 more source