XCIV.—The constitution of carbamides. Part IX. The interaction of nitrous acid and mono-substituted ureas. The preparation of diazomethane, diazoethane, diazo-n-butane, and diazoisopentane from the respective nitrosoureas [PDF]
Emil Alphonse Werner
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Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
CLXXXII.—The interaction of hydrogen dioxide and sulphides [PDF]
Maud Gazdar, Samuel Smiles
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Verification of protein structures: Patterns of nonbonded atomic interactions
Chris Colovos, T. Yeates
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Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
The Interaction of Riboflavin, FMN, and FAD with Various Metal Ions: The Riboflavin Catalyzed Photochemical Reduction of FeIII, and Photooxidation of FeII. [PDF]
William J. Rutter+5 more
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Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
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Molecular Interactions in Irradiated Solids
Amos Norman, William Ginoza
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Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source