Results 131 to 140 of about 940,273 (317)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Human Brain Atlas: Spinal Cord (Low Cervical) - Slide 105 - Labeled Outline

open access: yes, 2002
Anatomical structures of the spinal cord are identified in this labeled outline from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core  

The Evolution of E-Module Development in Secondary Education: A Systematic Review of Trends and Emerging Practices

open access: yesJurnal Paedagogy
This study aims to systematically examine the evolution of e-module development in secondary education between 2020 and 2024. Employing a Systematic Literature Review (SLR) method guided by the PRISMA 2020 protocol, the study explores emerging trends in ...
Annisa Nurbaiti   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Human Brain Atlas: Spinal Cord (Mid Cervical) - Slide 106 - Labeled

open access: yes, 2002
Anatomical structures of the spinal cord are identified in this labeled slide from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Human Brain Atlas: Spinal Cord (Sacral) - Slide 101

open access: yes, 2002
Anatomical structures of the spinal cord are depicted in this slide from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Human Brain Atlas: Brain Stem (Transverse) - Slide 8 - Labeled Outline

open access: yes, 2002
Anatomical structures of the brain stem are identified in this labeled outline from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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