Results 161 to 170 of about 3,422,311 (360)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Human Brain Atlas: Spinal Cord (Sacral) - Slide 101 - Labeled Outline
, 2002 Anatomical structures of the spinal cord are identified in this labeled outline from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
MRI Atlas: Brain (Axial) - Scan 6 - Labeled (Enlarged)
, 2002 Anatomical structures of the brain are identified in this scan with labeled outline from the UCLA Interactive Neurosciences MRI ...
The Regents of the University of California
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Human Brain Atlas: Brain Stem (Transverse) - Slide 32 - Labeled
, 2002 Anatomical structures of the brain stem are identified in this labeled slide from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
ilastik: interactive machine learning for (bio)image analysis
Nature Methods, 2019 S. Berg +18 more
semanticscholar +1 more source
Human Brain Atlas: Brain Stem (Transverse) - Slide 20 - Labeled Outline
, 2002 Anatomical structures of the brain stem are identified in this labeled outline from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source