Results 181 to 190 of about 3,422,311 (360)

Making The Most of Medical orientation; A New Approach.

open access: yesMedical Education Online, 2004
Orientating new junior medical staff can be a complex and time consuming task. Traditional models have typically involved a day or longer of lectures. This involves a large number of senior staff being available on the first day of term.
Dr Jonathan Taitz
doaj  

MRI Atlas: Brain (Axial) - Scan 5 - Labeled (Enlarged)

open access: yes, 2002
Anatomical structures of the brain are identified in this scan with labeled outline from the UCLA Interactive Neurosciences MRI ...
The Regents of the University of California
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Human Brain Atlas: Spinal Cord (Low Thoracic) - Slide 103

open access: yes, 2002
Anatomical structures of the spinal cord are depicted in this slide from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

"GrabCut": interactive foreground extraction using iterated graph cuts

open access: yesACM Transactions on Graphics, 2004
C. Rother, V. Kolmogorov, A. Blake
semanticscholar   +1 more source

Human Brain Atlas: Spinal Cord (Sacral) - Slide 101 - Labeled

open access: yes, 2002
Anatomical structures of the spinal cord are identified in this labeled slide from the UCLA Interactive Neurosciences Human Brain ...
The Regents of the University of California
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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