Results 81 to 90 of about 2,600,111 (291)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Case study in higher school: problems of application and efficiency estimation [PDF]
Современная зарубежная психология, 2015 Case study takes leading positions in training specialists at higher schools in the majority of foreign countries and is regarded as the most efficient way of teaching students how to solve typical professional tasks.
Ekimova V.I.
doaj
Multilingual interactive experiments with Flickr [PDF]
, 2006 This paper presents a proposal for iCLEF 2006, the interactive track of the CLEF cross-language evaluation campaign. In the past, iCLEF has addressed applications such as information retrieval and question answering.
Clough, Paul +2 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Towards Interactive Logic Programming [PDF]
, 2015 Linear logic programming uses provability as the basis for computation. In the operational semantics based on provability, executing the additive-conjunctive goal $G_1 \& G_2$ from a program $P$ simply terminates with a success if both $G_1$ and $G_2 ...
Kwon, Keehang, Park, Mi-Young
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Acquiring Knowledge in Learning Concepts from Electrical Circuits: The Use of Multiple Representations in Technology-Based Learning Environments [PDF]
Journal of Systemics, Cybernetics and Informatics, 2012 The constructivists approach on the conception of relative software of modelling to training and teaching of the concepts of current and voltage requires appraisal of several disciplinary fields in order to provide to the learners a training adapted to ...
Abdeljalil Métioui, Louis Trudel
doaj
Expect (and Collect) a Response From Everyone in the Classroom
Communications in Information Literacy, 2011 A positive and descriptive book review of Derek Bruff's 2009 book Teaching with Classroom Response Systems: Creating Active Learning Environments.
Karen Bronshteyn
doaj +1 more source