Results 91 to 100 of about 445,132 (266)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

مادة العربية وتطويرها ببرنامج التعلم التفاعلي لترقية قدرة الطلبة على مهارة الاستماع

open access: yesLisanuna: Jurnal Ilmu Bahasa Arab dan Pembelajarannya
This research addresses the listening problem students suffer from when studying listening skills. This problem is addressed by developing the listening material based on the interactive learning program as one of the modern educational methods.
azwir azwir   +2 more
doaj   +1 more source

Interactive Academic Education and Its Impact on Urban Development - History and Contemporaneousness

open access: yesReview of Artistic Education, 2019
Education for urban development is a process with a primary role to preserve and use of environment, to manage spatial planning and urban development as a whole holistic system.
Bajçinovci Bard   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Interactivity and thought [PDF]

open access: yes, 2011
A shared tenet of embodied, embedded, situated and distributed cognition is that people make sense of things interactively. They run a simulation, they exchange words, often taking turns to change and steer the flow of interaction; they gesture, they handle or manipulate things, they write, sketch or model.
Kirsh, David   +3 more
openaire   +2 more sources

Interaction Combinators

open access: yesInformation and Computation, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Deepening Mathematical Understanding Using Visualization and Interactive Learning for Deaf Students

open access: yesEngineering Proceedings
Learning mathematical concepts is challenging for several students. Paying attention to class lectures and following instructions for different steps to solve a problem are the keys to success in learning mathematical concepts.
Stefanie Amiruzzaman   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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