Results 81 to 90 of about 1,657,032 (289)
HBRC Journal, 2016 This research attempts to offer a new approach for architectural design process that the concepts of interaction and multi-relations are being achieved through it. This approach, which is identified as an interactive architecture, suggests a process that
Mojtaba Parsaee +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
An Interactive Approach for Hierarchical Parameter Optimization
Journal of Fluid Science and Technology, 2008 We propose a novel interactive parameter optimization technique which asks users to determine whether further exploration is required by using a hierarchical visualization technique. Our technique generates a k-d tree and uses the coefficient of multiple
Teppei TANAKA +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Jurnal Pedagogi dan PembelajaranMathematics is one of the subjects that is often encountered and has an important role in everyday life. Mathematics lessons will always be found at every level of education, both in elementary school and in college.
Ni Kadek Sri Widiari, I Wayan Wiarta
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cybergeo, 2006 Recent developments in interactive and dynamic cartography and development of Internet technologies have largely contributed to increase the number of interactive atlases on the Internet.
Philippe Apparicio, Valera Petkevitch
doaj +1 more source
A discriminative approach to grounded spoken language understanding in interactive robotics [PDF]
, 2016 Spoken Language Understanding in Interactive Robotics provides computational models of human-machine communication based on the vocal input. However, robots operate in specific environments and the correct interpretation of the spoken sentences depends ...
Basili, Roberto +4 more
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source