Results 141 to 150 of about 70,986 (299)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

GbyE: an integrated tool for genome widely association study and genome selection based on genetic by environmental interaction

open access: yesBMC Genomics
Background The growth and development of organism were dependent on the effect of genetic, environment, and their interaction. In recent decades, lots of candidate additive genetic markers and genes had been detected by using genome-widely association ...
Xinrui Liu   +8 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Characteristaion of the initial generations of recombinant inbred lines in perennial ryegrass (lolium perenne L.) using molecular markers and cytogenetics

open access: yes, 2009
Doctoral ThesisIn this study three early generations of a recombinant inbred line (RIL) breeding programme have been characterised by cytogenetic methods, metabolite profiling and a biomass quantitative trait loci (QTL) study. In situ hybridization was
Anhalt, Ulrike C. M.   +1 more
core  

INTERACTIVE METADISCOURSE IN FINDINGS SECTION AND DISCUSSION SECTION OF INTERNATIONAL JOURNAL ARTICLES [PDF]

open access: yes, 2017
Penelitian ini dilakukan untuk menginvestigasi penggunaan dan fungsi dari interactive metadiscourse pada bagian temuan dan pembahasan di dalam jurnal artikel internasional.
NABILAH FILZAH NUR WIJAYA, .
core  

The Role of Explicit Instruction of Interactive Metadiscourse Markers in Iranian EAP Learners’ Reading Comprehension

open access: yesEast European Journal of Psycholinguistics, 2014
This research was conducted to investigate the role that explicit instruction of interactive metadiscourse markers plays in Iranian EAP learners’ reading comprehension performance. To this end, 36 students of business management in intermediate level of
Javad Ahmadi Fatalaki   +2 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Gyaros Interactive: A 3D-Printed Multimedia Experience

open access: yes
Gyaros is a remote Greek island designated as a Marine Protected Area, with significant ecological value and a complex history as a former political prison, yet its isolation limits public engagement.
Monico, Dominic   +3 more
core  

Watershed from propagated markers to interactive segmentation of objects in image sequences [PDF]

open access: yes, 2018
Orientador: Roberto de Alencar LotufoTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de ComputaçãoResumo: Esta tese de doutorado apresenta um método interativo para segmentação de objetos em sequências de imagens -
Flores, Franklin Cesar
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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