Results 61 to 70 of about 1,031,896 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Large-Scale Complex Network Community Detection Combined with Local Search and Genetic Algorithm

open access: yesApplied Sciences, 2020
With the development of network technology and the continuous advancement of society, the combination of various industries and the Internet has produced many large-scale complex networks.
Desheng Lyu, Bei Wang, Weizhe Zhang
doaj   +1 more source

Head–Media Interaction in Magnetic Recording [PDF]

open access: yesJournal of Differential Equations, 2001
The tape head interaction in magnetic recording is modelled by a coupled system of a second order differential equation for the pressure and a fourth-order differential equation for the tape deflection. There is also the constraint that the spacing between the head and tape remains positive.
Tello del Castillo, José Ignacio   +1 more
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Extended Reality Educational System with Virtual Teacher Interaction for Enhanced Learning

open access: yesMultimodal Technologies and Interaction
Advancements in technology that can reshape educational paradigms, with Extended Reality (XR) have a pivotal role. This paper introduces an interactive XR intelligent assistant featuring a virtual teacher that interacts dynamically with PowerPoint ...
Fotis Liarokapis   +2 more
doaj   +1 more source

The case against the democratic influence of the internet on journalism [PDF]

open access: yes, 2009
Book synopsis: Web Journalism: A New Form of Citizenship provides a much-needed analytical account of the implications of interactive participation in the construction of media content. Although web journalism is a fast-changing technology this book will
Markham, Tim
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Objective measurement of AI literacy: Development and validation of the AI competency objective scale (AICOS)

open access: yesComputers and Education: Artificial Intelligence
As Artificial Intelligence (AI) becomes increasingly pervasive in everyday life, AI literacy is widely recognized as a set of essential competencies for navigating AI-driven environments safely, responsibly, and effectively.
André Markus   +2 more
doaj   +1 more source

A Typographic Dilemma: Reconciling the old with the new using a new cross-disciplinary typographic framework [PDF]

open access: yes, 2004
Current theory and vocabulary used to describe typographic practice and scholarship are based on a historically print-derived framework. As yet, no new paradigm has emerged to address the divergent path that screen-based typography is taking from its ...
Yee, Joyce
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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