Results 251 to 260 of about 64,319 (300)

Intercalators as Anticancer Drugs

Current Pharmaceutical Design, 2001
Intercalators are the most important group of compounds that interact reversibly with the DNA double helix. Some of them are valuable drugs currently used for the treatment of ovarian and breast cancers and acute leukemias, while many others are in different phases of clinical trials.
M F, Braña, M, Cacho, A, Gradillas, B, de Pascual-Teresa, A, Ramos   +4 more
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Harnessing DNA intercalation

Trends in Biotechnology, 2007
Numerous small molecules are known to bind to DNA through base pair intercalation. Fluorescent dyes commonly used for nucleic acid staining, such as ethidium, are familiar examples. Biological and physical studies of DNA intercalation have historically been motivated by mutation and drug discovery research.
Ozgül, Persil, Nicholas V, Hud
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Intercalation compounds of graphite

Advances in Physics, 1981
AbstractFor Abstract see ChemInform Abstract in Full Text.
M. S. Dresselhaus, G. Dresselhaus
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Alprazolam Intercalates into DNA

Journal of Biomolecular Structure and Dynamics, 2009
In vitro interaction of a benzodiazepine group of drugs Alprazolam (Alp), a hypnotic and tranquilizer, with DNA was studied by various methods. Absorption spectrophotometric study showed that Alp binds strongly with supercoiled pUC 19 DNA and the calculated binding constant is 8.245x10(3) M(-1) in 10 mM Tris-Cl buffer, pH 7.4. Spectrofluorometric study
Biswarup, Saha, Ananda, Mukherjee, Chitta Ranjan, Santra, Atiskumar, Chattopadhyay, Amar Nath, Ghosh, Utpal, Choudhuri, Parimal, Karmakar   +6 more
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An octakis-intercalating molecule

Bioorganic & Medicinal Chemistry, 2001
Herein we report the synthesis and characterization of a polyintercalator with eight potential intercalating l,4,5,8-naphthalenetetracarboxylic diimide (NDI) units linked in a head-to-tail arrangement via a peptide linker. UV spectroscopy and viscometry measurements indicated the molecule binds to double-stranded DNA with all eight NDI units ...
M M, Murr, M T, Harting, V, Guelev, J, Ren, J B, Chaires, B L, Iverson   +5 more
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Lithium intercalation in LixZrS2

Solid State Communications, 1984
We report electrochemical and x-ray diffraction studies of LixZrS2. lT-ZrS2 undergoes a reversible first order transition to the 3R polytype when intercalated with lithium. Co-existing 1T and 3R phases are observed for 0.01 ± 0.01 < x < 0.23 ± 0.01.
J.R. Dahn, W.R. McKinnon, C. Levy-Clement   +2 more
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Intercalating in global health

Veterinary Record, 2015
After finishing her third year of veterinary studies at the Royal Veterinary College, Helena Diffey decided to intercalate in global health at Imperial College, London.
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Intercalation of Benzamide into Kaolinite

Journal of Colloid and Interface Science, 2000
Well-crystallized kaolinite (K) was initially reacted at 60 degrees C with a water/dimethylsulfoxide (DMSO) mixture and the resulting intercalation derivative (K-DMSO) was characterized by powder X-ray diffractometry (PXRD), thermal analysis (simultaneous TG and DSC), and Fourier-transformed infrared spectroscopy (FTIR).
, Gardolinski, , Ramos, , de Souza GP, , Wypych   +3 more
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Intercalation of phenylethylamines into?-zirconium phosphate and characterization of intercalates

Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, 1991
The intercalation of phenylethylamines intoα-zirconium phosphate has been investigated by the pH titration method.dl-1-Phenylethylamine (dl-PEA) is taken up in two stages. New phases were obtained: Zr(HPO4)2(dl-PEA) · H2O in the first, and Zr(HPO4)2(dl-PEA)/43· H2O in the second stage.
Yoshitsugu Hasegawa, Hisashi Seki, Isao Tomita   +2 more
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Superconductivity in Alkali Intercalated C60

Materials Science and Engineering: B, 1992
A model for superconductivity in alkali intercalated C60 is proposed. The key to the high observed transition temperatures is the molecular nature of fullerite. Two different energy scales tintra/tinter ≳ 5–10 for electron hopping on the balls and between balls respectively allow for a large electron phonon coupling constant λ = 2 N · V.
M. SCHLÜTER, M. LANNOO, M. NEEDELS, G.A. BARAFF, D. TOMÁNEK   +4 more
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