Results 31 to 40 of about 36,290 (266)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Superstoichiometric reversible and manipulable copper-ion intercalation in niobium selenide

open access: yesNature Communications
Few-layer stacked niobium selenide (NbSe2) has evoked great interest owing to its intrinsically exotic properties and accessible manipulation by controlled ion intercalation for superconductivity physics and advanced device applications.
Yuanhe Sun   +12 more
doaj   +1 more source

Impact of Pretreatment of the Bulk Starting Material on the Efficiency of Liquid Phase Exfoliation of WS2

open access: yesNanomaterials, 2021
Liquid phase exfoliation (LPE) is widely used to produce colloidal dispersions of nanomaterials, in particular two-dimensional nanosheets. The degree of exfoliation, i.e., the length to thickness aspect ratio was shown to be intrinsically limited by the ...
Steffen Ott   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Intercalation of Cocamide Diethanolamine into Swellable Clay by Solid-State Process

open access: yesCrystals, 2022
Coconut fatty acid diethanolamine (cocamide-DEA (CDEA)), CH3(CH2)16CON(CH2CH2OH)2 was intercalated into montmorillonite using both solution and solid-state reaction methods.
Yang-Su Han, In Park
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

Preparation of Crown Ether Pillared Zirconium Phosphonate and Selective Adsorption for Strontium

open access: yesJournal of Isotopes, 2021
Separation of strontium isotope is an important and challenging work. Herein, a novel method was developed for preparing of acid-resistance crown ether pillared zirconium phosphonate (D-AM-ZrP) by a directly one step reacting 4-amino-benzo-18-crown-6 ...
MU Wanjun;WEI Hongyuan;CHEN Baihua;LI Xingliang;YANG Yuchuan;PENG Shuming
doaj   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth   +8 more
wiley   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy