Results 81 to 90 of about 167,182 (276)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Association of adipokines and adhesion molecules with indicators of obesity in women undergoing mammography screening

Nutrition & Metabolism, 2012
Background The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis.
Isoppo de Souza Caroline, Rosa Daniela Dornelles, Ettrich Betina, Cibeira Gabriela Hermann, Giacomazzi Juliana, Tusset Paloma, Ashton-Prolla Patrícia, Medeiros Lidia Rosi, Caleffi Maira, Neto Eurico Camargo, Moriguchi Emilio Hideyuki, Graudenz Marcia Silveira   +11 more
doaj   +1 more source

Cryptotanshinone attenuates in vitro oxLDL-induced pre-lesional atherosclerotic events. [PDF]

, 2011
Development of early stage atherosclerosis involves the activation of endothelial cells by oxidized low-density lipoprotein (oxLDL) with subsequent increases in endothelial permeability and expression of adhesion molecules favoring the adherence of ...
Abd. Kadir, Arifah, Ahmad, Zuraini, Ang, Kok Pian, Md. Akim, Abdah, Selvaraja, Malarvilli, Somchit, Muhammad Nazrul, Tan, Heng Kean, Zakaria, Zainul Amiruddin   +7 more
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Blood Adhesion Molecules as Biomarkers in Children with Chronic Urticaria

Children
Background: The prevailing etiological model of both acute and chronic urticaria implicates specific allergen exposure that triggers the local release of vasoactive factors and inflammatory adhesion molecules, including vascular cell adhesion molecule 1 (
Ioanna Angeli, Emilia Vassilopoulou, Dimitrios Cassimos, Ioannis Fotopoulos, Anastasios Serbis, Makis Alexandros, Sophia Tsabouri   +6 more
doaj   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

The Effect of Eight Weeks of Continuous Endurance Training on ICAM-1 and VCAM-1 Expression in the Heart Tissue of Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2019
BACKGROUND AND OBJECTIVE: The expression of adhesion molecules in the heart tissue is considered as an important indicator in the estimation of coronary artery disease risk.
MR Asad, M Sistani, A Barzegari
doaj  

Suppresses of Astragalus Polysaccharide on E. coli-Induced Injured Intestinal Microvascular through TLR4-NF-κB Signal Pathways in Chickens [PDF]

Brazilian Journal of Poultry Science, 2019
To investigate the hypothesis that APS can attenuate E. coli-induced microvascular dysfunction in chicken intestine, 60 0-day old male chickens were divided into three groups with 5 replications of 4 chicks.
L Su, J Wang, J Huang, Y Zhao, H Jiang, H Li   +5 more
doaj   +1 more source

Intercellular adhesion molecule-1 mediates murine colon adenocarcinoma invasion [PDF]

Journal of Surgical Research, 2014
Intercellular adhesion molecule-1 (ICAM-1) modulates cell-cell adhesion and is a receptor for cognate ligands on leukocytes. Upregulation of ICAM-1 has been demonstrated in malignant transformation of adenomas and is associated with poor prognosis for many malignancies. ICAM-1 is upregulated on the invasive front of pancreatic metastases and melanomas.
Kenton, Howard, Karen K, Lo, Lihua, Ao, Fabia, Gamboni, Barish H, Edil, Richard, Schulick, Carlton C, Barnett   +6 more
openaire   +2 more sources

Inflammatory mediators and cell adhesion molecules as indicators of severity of atherosclerosis: the Rotterdam Study [PDF]

, 2002
Inflammatory mediators and soluble cell adhesion molecules predict cardiovascular events. It is not clear whether they reflect the severity of underlying atherosclerotic disease.
Bots, M.L. (Michiel), Breteler, M.M.B. (Monique), Hofman, A. (Albert), Kiliaan, A.J. (Amanda), Maat, M.P.M. (Moniek) de, Meijer, J. (John), Witteman, J.C.M. (Jacqueline)   +6 more
core