Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source
Multi-Kingdom Synergy of <i>Perilla frutescens</i>-Derived Effector Vesicles and Postbiotics: A Triple-Action Strategy for Atopic Dermatitis. [PDF]
Badale A +4 more
europepmc +1 more source
Marine silicon for biomedical sustainability
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han +3 more
wiley +1 more source
Apoptotic extracellular vesicles act as master regulators of the bone healing niche. [PDF]
Guo Y +7 more
europepmc +1 more source
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Mechanical forces from intercellular peptide self-assembly drive spheroid formation. [PDF]
Lu H +7 more
europepmc +1 more source
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Mitochondrial-Immune Dysfunction in MS: Therapeutic Potential of EV-Mediated Transfer. [PDF]
Navazi P, Fereidouni M, Erfanian N.
europepmc +1 more source
Atomically precise metal cluster enzymes for pathological tissue regeneration
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong +11 more
wiley +1 more source
Nanotherapy for Pancreatitis: From Single-Cell Targeting Toward Multicellular-Coordinated Regulation. [PDF]
Li BF, Li XH, Deng Y, Deng J, Zhang XM.
europepmc +1 more source

