Results 21 to 30 of about 48,889 (290)

Efficacy and Safety in the Continued Treatment With a Biosimilar Drug in Patients Receiving Infliximab: A Systematic Review in the Context of Decision-Making From a Latin-American Country

open access: yesFrontiers in Pharmacology, 2019
Introduction: Biological products, including infliximab (INF), are a therapeutic option for various medical conditions. In the Peruvian Social Security (EsSalud), infliximab is approved for the treatment of rheumatoid arthritis, psoriasis, psoriatic ...
Edward Mezones-Holguin   +8 more
doaj   +1 more source

Digital interchangeability design of aircraft control surfaces

open access: yesHangkong gongcheng jinzhan
With the gradual maturity and application of digital assembly technology,the interchangeability design adapting to digital quantity transfer is of significant practical significance for improving the efficiency of aircraft control surface design ...
LI Yunpeng, YAO Xionghua, GAO Shuai
doaj   +1 more source

Comparison of Hematological and Biochemical Results Derived from Arterial and Venous Blood Samples in Post-Anesthetic Dogs

open access: yesAnimals, 2020
Collecting blood from an indwelling arterial catheter may reduce stress from repeated venipuncture in patients requiring serial monitoring, but the use of arterial blood for hematological and biochemical testing remains understudied.
Song Mi Lee   +3 more
doaj   +1 more source

An Empirical Analysis of the Perceived Challenges and Benefits of Introducing Biosimilars in Bangladesh: A Paradigm Shift

open access: yesBiomolecules, 2018
The high demand for and resulting financial success of biopharmaceutical products over the last three decades have seen the door open for close copies of these biological products, also known as biosimilars.
Eva Rahman Kabir   +2 more
doaj   +1 more source

Successful implementation of interchange of biologic medications in chronic arthritis after information of costs to prescribers [PDF]

open access: yesExploration of Musculoskeletal Diseases
Aim: To evaluate the impact of prescription, cost, and switching policy on the rate of switching from reference products to biosimilars. Methods: Analysis of an administrative database for prescription in a rheumatology division.
Fernando Perez-Ruiz   +8 more
doaj   +1 more source

Biologics and biosimilars in musculoskeletal diseases: addressing regulatory inconsistencies and clinical uncertainty [PDF]

open access: yesExploration of Musculoskeletal Diseases
Biologics are complex protein-based medications derived from living organisms, used primarily to treat immune-related diseases. Unlike small-molecule drugs synthesized from chemicals, biologics are produced using advanced biotechnology, making their ...
Lauren N. McGrath   +2 more
doaj   +1 more source

Experimental Evaluation of Interchangeability in Soft CSPs [PDF]

open access: yes, 2006
In [8], Freuder defined interchangeability for classical Constraint Satisfaction Problems (CSPs). Recently [2], we extended the definition of interchangeability to Soft CSPs and we introduced two notions of relaxation based on degradation # and on ...
Boi Faltings   +2 more
core  

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

Concepts and Challenges of Biosimilars in Breast Cancer: The Emergence of Trastuzumab Biosimilars

open access: yesPharmaceutics, 2018
With the development of anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibodies, trastuzumab-based therapy has become the standard of care among patients with early or advanced HER2-positive breast cancer. However, real-world data have
Alina Uifălean   +5 more
doaj   +1 more source

A Partial Taxonomy of Substitutability and Interchangeability [PDF]

open access: yes, 2010
Substitutability, interchangeability and related concepts in Constraint Programming were introduced approximately twenty years ago and have given rise to considerable subsequent research.
Berthe Y. Choueiry   +8 more
core   +3 more sources

Home - About - Disclaimer - Privacy