Results 51 to 60 of about 63,556 (301)

Aspects of Hydrogen and Biomethane Introduction in Natural Gas Infrastructure and Equipment

open access: yesHydrogen, 2021
The injection of green hydrogen and biomethane is currently seen as the next step towards the decarbonization of the gas sector in several countries.
Filipe M. Quintino   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Recommendations on the procedure for determining the interchangeability of medicinal products

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The authors developed and presented recommendations on the procedure for determining the interchangeability of medicinal products. Interchangeability of drugs determined at the state registration of the medicinal product or when amendments to the ...
B. K. Romanov   +12 more
doaj  

Statistical Mechanics and Thermodynamics: Boltzmann’s versus Planck’s State Definitions and Counting

open access: yesEntropy, 2021
During the physical foundation of his radiation formula in his December 1900 talk and subsequent 1901 article, Planck refers to Boltzmann’s 1877 combinatorial-probabilistic treatment and obtains his quantum distribution function, while Boltzmann did not.
Peter Enders
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Interchangeability of cardiac output measurements between non-invasive photoplethysmography and bolus thermodilution: A systematic review and individual patient data meta-analysis.

open access: yesAnaesthesia Critical Care & Pain Medicine, 2020
BACKGROUND Continuous non-invasive cardiac output devices using digital photoplethysmography (PPG) are widely available for bedside use, but their interchangeability with reference methods has not yet been evaluated in a systematic review and patient ...
M. Fischer   +12 more
semanticscholar   +1 more source

Biosimilars for Rheumatoid Arthritis: Riding the 2023 Wave [Podcast]

open access: yesOpen Access Rheumatology: Research and Reviews, 2023
Stanley B Cohen,1,* Mariah Z Leach2,* 1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA; 2Mamas Facing Forward, Louisville, Colorado, USA*These authors contributed equally to this ...
Cohen SB, Leach MZ
doaj  

Real life hexavalent vaccination among children as a practical guide for public health professionals: Four years (from 2016 to 2019) of clinical practice in Sicily, Italy

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Hexavalent (HV) vaccination is a priority for newborn protection and in Italy is included in the National Immunization Plan with a three doses cycle at 61, 121 and 301 days of age.
Claudio Costantino   +17 more
doaj   +1 more source

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