Results 41 to 50 of about 135,005 (314)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Interconnected network of cameras [PDF]
SPIE Proceedings, 2013 The Panoptic camera is an omnidirectional multi-aperture visual system which is realized by mounting multiple imaging sensors on a hemispherical frame. Previously, centralized hardware implementation was demonstrated for the Panoptic camera. In this chapter, we present a novel distributed and parallel implementation of the real-time omnidirectional ...
Hosseini Kamal, Mahdad +4 more
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Journal of Computer and System Sciences, 1993 The problem of interconnecting circuit modules in microprocessor and digital system design is studied. Data transfers are described by sets \(T_ i\) of directed edges between the modules, for \(1\leq i\leq m\) time steps. An interconnecting schema, where data transfers are assigned to buses, consists of links between modules and buses.
openaire +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Interconnection networks for parallel and distributed computing [PDF]
, 2008 Parallel computers are generally either shared-memory machines or distributed- memory machines. There are currently technological limitations on shared-memory architectures and so parallel computers utilizing a large number of processors tend tube ...
Xiang, Yonghong
core
The Journal of Engineering, 2019 This article presents an extended backstepping control method to reduce the grid-side current harmonics caused by grid voltage distortion. A dynamic model considering the grid voltage as an external disturbance is derived in the stationary reference ...
Hang Yin +3 more
doaj +1 more source
Applied Mathematics Letters, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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