Results 41 to 50 of about 7,005,359 (300)
A High Static Performance Hierarchical Three-Dimensional Shifted Completely Connected Network
In recent years, there has been a significant shift toward the adoption of the “Internet of Things (IoT)” era, in which vast amounts of data are collected and processed, and Artificial intelligence (AI) is used to make critical choices ...
Mohammed N. M. Ali +4 more
doaj +1 more source
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Jean-Claude Bermond, Fahir Ö. Ergincan
openaire +2 more sources
Data center interconnection networks are not hyperbolic
Topologies for data center interconnection networks have been proposed in the literature through various graph classes and operations. A common trait to most existing designs is that they enhance the symmetric properties of the underlying graphs. Indeed,
D. Coudert, G. Ducoffe
semanticscholar +1 more source
Efficient and Cost-Effective Hybrid Congestion Control for HPC Interconnection Networks
Interconnection networks are key components in high-performance computing (HPC) systems, their performance having a strong influence on the overall system one.
J. Escudero-Sahuquillo +7 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Topological Properties of Hierarchical Interconnection Networks: A Review and Comparison
Hierarchical interconnection networks (HINs) provide a framework for designing networks with reduced link cost by taking advantage of the locality of communication that exists in parallel applications. HINs employ multiple levels.
Mostafa Abd-El-Barr, Turki F. Al-Somani
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

