Results 41 to 50 of about 169,756 (294)

Network interconnection with competitive transit [PDF]

Information Economics and Policy, 2004
Abstract We examine the interaction between two interconnected networks (e.g., two local exchange carriers (LECs)) and a third network (e.g., an interexchange carrier (IXC)) seeking access to their customer base. The IXC could either interconnect with both LECs or interconnect with only one LEC and transit calls to the other LEC via the first LEC's ...
David Gilo, Yossi Spiegel
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Topological Properties of Hierarchical Interconnection Networks: A Review and Comparison

Journal of Electrical and Computer Engineering, 2011
Hierarchical interconnection networks (HINs) provide a framework for designing networks with reduced link cost by taking advantage of the locality of communication that exists in parallel applications. HINs employ multiple levels.
Mostafa Abd-El-Barr, Turki F. Al-Somani
doaj   +1 more source

Synchronization in interacting Scale Free Networks [PDF]

, 2015
We study the fluctuations of the interface, in the steady state, of the Surface Relaxation Model (SRM) in two scale free interacting networks where a fraction $q$ of nodes in both networks interact one to one through external connections. We find that as
Braunstein, L. A., Di Muro, M. A., La Rocca, C. E., Torres, M. F.   +3 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Analysis and dynamic modeling of firing synchronization in electrically interconnected dual-compartment neuronal networks

Microsystems & Nanoengineering
In vitro cultured neuronal networks offer controllable experimental models for investigating neuronal information processing mechanisms and network plasticity.
Chengji Lu, Longhui Jiang, Qianli Jia, Peiyao Jiao, Shuqi Li, Shutong Sun, Jinping Luo, Mixia Wang, Xinxia Cai, Yirong Wu   +9 more
doaj   +1 more source

Constructing Independent Spanning Trees on Transposition Networks

IEEE Access, 2020
In interconnection networks, data distribution and fault tolerance are crucial services. This study proposes an effective algorithm for improving connections between networks.
Chien-Fu Lin, Jie-Fu Huang, Sun-Yuan Hsieh   +2 more
doaj   +1 more source

Lowest common ancestor interconnection networks [PDF]

, 1992
Lowest Common Ancestor (LCA) networks are built using switches capable of connecting u + d inputs/outputs in a permutation pattern. For n source nodes and I stages of switches, n/d switches are used in stage l - n/d - u/d in stage l - 2, and in general ,
Alleyne, Brian D., Chien, Chi-Kai, Scherson, Isaac D.   +2 more
core