Results 51 to 60 of about 169,756 (294)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Network traffic behaviour near phase transition point [PDF]

open access: yes, 2005
We explore packet traffic dynamics in a data network model near phase transition point from free flow to congestion. The model of data network is an abstraction of the Network Layer of the OSI (Open Systems Interconnection) Reference Model of packet ...
Lawniczak, Anna T., Tang, Xiongwen
core   +2 more sources

Nanotube-interconnected liposome networks

open access: yesNano Communication Networks, 2011
Tunneling phospholipid nanotubes between animal cells have recently been identified as a major building block in an important fundamental mechanism of cell-to-cell communication. In order to gain deeper understanding of this interaction and other micro- and nanoscale phenomena connected to material transport and communication in the living world, cell ...
Wegrzyn, Ilona   +3 more
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Security in transnational interoperable PPDR communications: threats and requirements [PDF]

open access: yes, 2015
The relevance of cross border security operations has been identified as a priority at European level for a long time. A European network where Public Protection and Disaster Relief (PPDR) forces share communications processes and a legal framework ...
Duits, Michel   +9 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

FleX: A Flex Interconnected HPC System With Stochastic Load Balancing Scheme

open access: yesIEEE Access, 2022
We propose a new low-diameter interconnection network called FleX, which offers high flexibility when installing interconnections in a HPC system. FleX consists of multiple layers with only connections between neighboring layers and not within each layer.
Minsu Jeon   +4 more
doaj   +1 more source

Analysis of searching mechanisms in hierarchical p2p based overlay networks [PDF]

open access: yes, 2007
Proceedings of: The 6th Annual Mediterranean Ad Hoc Networking Workshop (Med Hoc Net 2007. (Corfu, Greece), June 2007This work presents a study of searching mechanisms in Peer-to-Peer (p2p) networks.
Cuevas, Rubén   +3 more
core   +1 more source

Support Service for Reciprocal Computational Resource Sharing in Wireless Community Networks [PDF]

open access: yes, 2013
In community networks, individuals and local organizations from a geographic area team up to create and run a community-owned IP network to satisfy the community's demand for ICT, such as facilitating Internet access and providing services of local ...
Buyuksahin, Umit C   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy