Results 31 to 40 of about 44,369 (265)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Promises and pitfalls of China-Southeast Asia energy connectivity
Energy Strategy Reviews, 2021 China offers the Global Energy Interconnections (GEI) as a planetary project to deliver sustainable development and climate action through large-scale energy transition by interconnecting most of the world's grids. What does this mean for Southeast Asian
Laurence L. Delina
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
From interconnections of local electric power systems to Global Energy Interconnection
Global Energy Interconnection, 2018 The interconnections of electric power systems are developed for the economic benefits and in order to increase the overall power supply reliability and quality level.
Nikolai Voropai +2 more
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Processor Interconnection Strategies [PDF]
IEEE Transactions on Computers, 1980 In this paper, we describe four families of topologies for interconnecting many identical processors into a computer network. Each family extends to arbitrarily many processors while keeping the number of neighbors of any one processor fixed. These families are investigated with respect to bus load, routing algorithms, and the relation between the ...
Raphael A. Finkel, Marvin H. Solomon
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Autoimmune disease and interconnections with vitamin D
Endocrine Connections, 2022 Vitamin D has well-documented effects on calcium homeostasis and bone metabolism but recent studies suggest a much broader role for this secosteroid in human health.
Jane Fletcher +7 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Interconnections between Inflammageing and Immunosenescence during Ageing
Cells, 2022 Acute inflammation is a physiological response to injury or infection, with a cascade of steps that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal wounds.
Thibault Teissier +2 more
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Applied Mathematics Letters, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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