Results 51 to 60 of about 44,523 (265)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
THE IMPACT OF TRANSMISSIONS 110 kV ON THE LEVEL OF POWER LOSSES IN MOLDAVIAN POWER SYSTEM
Problems of the Regional Energetics, 2012 The paper present the simulation results of system operation in conditions of energy exchange with Ukraine considering the level of power losses in Moldova.
Kalinin L. +3 more
doaj
Raman Investigation on Silicon Nitride Chips after Soldering onto Copper Substrates
MicromachinesThe unique electrical properties of silicon nitride have increased the applications in microelectronics, especially in the manufacture of integrated circuits.
Claudia Mezzalira +3 more
doaj +1 more source
The Heterogeneous Interconnections between Supply or Demand Side and Oil Risks
Energies, 2019 Due to the crucial implication of oil risks for economic growth and policy making, the aim of this paper is to explore the heterogeneous interconnections of supply or demand in oil risks over time horizons and different countries.
Gaoke Liao +3 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
STRUCTURAL INTERCONNECTIONS OF THE SUBJECTS OF CIRCULATION
Соціальна економіка, 2020 The aim of the article is justification of the classification of subjects in a sphere of circulation of goods, which is due to their significant diversity, which is associated with the content of the process of promoting the final product from the ...
Serhii Tkachenko
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Scientific Reports, 2021 With the rapid development of stretchable and wearable technologies, stretchable interconnection technology also demanded along it. Stretchable interconnections should have high stretchability and stable conductivity for use as an electrode. In addition,
Min Ju Yun +3 more
doaj +1 more source
Journal of Computer and System Sciences, 1993 The problem of interconnecting circuit modules in microprocessor and digital system design is studied. Data transfers are described by sets \(T_ i\) of directed edges between the modules, for \(1\leq i\leq m\) time steps. An interconnecting schema, where data transfers are assigned to buses, consists of links between modules and buses.
openaire +2 more sources