Results 51 to 60 of about 200,909 (285)

An economic benefit evaluation model and its application for optimizing transmission capacity of multinational interconnections

open access: yesCSEE Journal of Power and Energy Systems, 2018
Multinational power grid interconnections play a critical part in supporting the vision of global energy internet. During the early stages of the Global Energy Internet, the value proposition of multinational interconnections should be carefully ...
Xiaojun Wang   +4 more
doaj   +1 more source

Leveraging interconnections for performance: the serving infrastructure of a large CDN

open access: yesConference on Applications, Technologies, Architectures, and Protocols for Computer Communication, 2018
Today's large content providers (CP) are busy building out their service infrastructures or "peering edges" to satisfy the insatiable demand for content created by an ever-expanding Internet edge.
F. Wohlfart   +4 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Dynamic Overload Capability of VSC HVDC Interconnections for Frequency Support

open access: yesIEEE transactions on energy conversion, 2017
In future power systems, reduced overall inertia caused by an increased dominance of asynchronous generation and interconnections would make frequency control particularly challenging. As the number and power rating of voltage source converter (VSC) HVDC
I. M. Sanz   +4 more
semanticscholar   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

THE IMPACT OF TRANSMISSIONS 110 kV ON THE LEVEL OF POWER LOSSES IN MOLDAVIAN POWER SYSTEM

open access: yesProblems of the Regional Energetics, 2012
The paper present the simulation results of system operation in conditions of energy exchange with Ukraine considering the level of power losses in Moldova.
Kalinin L.   +3 more
doaj  

World Decarbonization through Global Electricity Interconnections

open access: yesEnergies, 2018
The challenge of worldwide energy decarbonization is crucial to ensure sustainable development. The achievement of decarbonization encompasses not only a considerable exploitation of renewable energy sources, but also a paradigm shift in final energy ...
Ettore Bompard   +5 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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