Results 21 to 30 of about 1,801,902 (300)

Information literacy as part of an interdisciplinary approach to combat misinformation

Information Research: An International Electronic Journal
Introduction. Misinformation is a complex challenge that cuts across all fields and thus requires an interdisciplinary solution. As professionals who support information access and evaluation across fields and have long-championed information literacy ...
Laura Saunders
doaj   +1 more source

Role of Multidisciplinary and Interdisciplinary Education in Computer Science: A Literature Review [PDF]

Managing Global Transitions, 2018
Disruption of economies, caused by the Internet and communications technology and its effect to other industries, has had and will continue to have severe effect to the existing business models and production of goods for the upcoming decades.
Kari-Pekka Heikkinen, Teppo Räisänen
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Boundary Spanning in Academia: Antecedents and Near-Term Consequences of Academic Entrepreneurialism [PDF]

, 2013
Analyzing the pathways of people who earned interdisciplinary research doctorates in the United States in 2010, we generate three main findings while controlling for gender, ethnicity, discipline, and age.
Hanks, Andrew S, Kniffen, Kevin M
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Mathematician's call for interdisciplinary research effort [PDF]

, 2013
The article addresses the necessity of increasing the role of mathematics in the psychological intervention in problem gambling, including cognitive therapies. It also calls for interdisciplinary research with the direct contribution of mathematics.
Barboianu, Catalin
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

“I Learned How to Think, Not What to Think.” Student Perspectives on an Interdisciplinary Undergraduate Honours Programme

Canadian Journal for the Scholarship of Teaching and Learning
The Arts and Science Honours Academy (ASHA) is a unique interdisciplinary undergraduate honours programme at a large research-intensive university in Canada.
Jenny Godley, Lori Jane Pasaraba, Megan Wilson, Mabel Teye-Kau, Mark Migotti   +4 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source