Results 161 to 170 of about 8,948,996 (287)

Decoupling Stable Cyclic Deformation From Defect Accumulation in Metals

open access: yesAdvanced Science, EarlyView.
Introducing amorphous nanoparticles into a metal matrix enables a cyclic deformation regime where strain hardening and defect accumulation are decoupled. These nanoparticles act as dislocation sinks and undergo reversible shear transformations, sustaining microstructural stability over millions of cycles.
Chenjun Ye   +9 more
wiley   +1 more source

Acinar‐Derived Organoids Reveal Stage‐Specific Control of Acinar Plasticity

open access: yesAdvanced Science, EarlyView.
An acinar‐derived organoid system maintains adult pancreatic acinar identity ex vivo, converts it along an ordered acinar‐to‐ductal‐like trajectory, and then partially restores it. Each transition carries its own signal requirement, with EGF/EGFR initiating conversion and a staged glucocorticoid–IGF1R switch driving redifferentiation.
Yongfei Hou   +10 more
wiley   +1 more source

Polyphosphate Copper Nanospheres Drive Mitochondrial Metabolic Reprogramming via Calcium Phase Separation for Self‐Sensitizing Cuproptosis

open access: yesAdvanced Science, EarlyView.
This study developed polyphosphate (polyP)‐based nanostructures that enable calcium‐mediated metabolic reprogramming via liquid–liquid phase separation (LLPS). Released polyP undergoes LLPS with Ca2+, suppressing glycolytic flux and enhancing mitochondrial metabolism effectively.
Jing Wang   +10 more
wiley   +1 more source

Pennsylvania Consortium For Interdisciplinary Environmental Policy

open access: yes
The Pennsylvania Consortium for Interdisciplinary Environmental Policy stresses the need for a "forum for collaboration on environmental policy and education." This site features an organization comprised of environmental policy makers and ...

core   +1 more source

Flooding‐Driven Greenhouse Gas Emissions From Global Upland Croplands

open access: yesAdvanced Science, EarlyView.
Temporary flooding of upland croplands releases nitrous oxide, carbon dioxide, and methane. Field measurements combined with a global literature synthesis yield a global estimate of 63.3 teragrams of carbon dioxide equivalent per year for diffusive emissions from flooded upland croplands.
Shuilian Bi   +7 more
wiley   +1 more source

Multiscale Interfacial Engineering Enables Robust Reconstituted Wood

open access: yesAdvanced Science, EarlyView.
Conventional adhesives used in wood composites create heterogeneous interfaces that cause stress concentration under humid or aqueous conditions, thereby compromising long‐term stability. A synergistic strategy integrating interfacial reconstruction and water‐induced regeneration transforms heterogeneous interfaces into homogeneous ones with ...
Huizheng Wu   +11 more
wiley   +1 more source

An Explainable Multimodal Deep‐Learning Model Using Histopathological Image and Clinical Information for Prognosis Prediction in Colorectal Cancer: A Multi‐Center Cohort Study

open access: yesAdvanced Science, EarlyView.
This study develops a multimodal deep‐learning model that integrates clinical variables and histopathological images to predict survival outcomes in colorectal cancer. The multimodal model effectively stratifies patients into low‐ and high‐risk groups, demonstrating superior accuracy and generalizability across multiple independent cohorts.
Zhihan Jiang   +12 more
wiley   +1 more source

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