Results 201 to 210 of about 18,639,208 (342)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A match made in health care: can ethics and governance better support impactful implementation research? [PDF]

Med J Aust
Taylor N, Li Z, van Kemenade C, Curtis J, Bolton P.   +4 more
europepmc   +1 more source

RESOLVING CONFLICTS OF INTEREST AND IDEOLOGIES: A SIMULATION OF POLITICAL DECISION-MAKING

, 1983
Rhonda Love, Richard M. Rozelle, Daniel Druckman   +2 more
openalex   +1 more source

Aligning interests [PDF]

Nature Biotechnology, 2008
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Differential effects of external noise and situational interest on neurophysiological responses during video based learning. [PDF]

NPJ Sci Learn
Levy O, Shadi T, Korisky A, Bleichner MG, Zion Golumbic E.   +4 more
europepmc   +1 more source

Patent-holders on expert committees. Can there be a conflict of interest?

, 2015
Erik Thorstensen
openalex   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Exploring the Potential Link Between Tirzepatide and Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): Evidence from FAERS and Google Trends. [PDF]

Hosp Pharm
Castellana E, Chiappetta MR.
europepmc   +1 more source

Decolonising Jurisprudence: Public Interest Standing in New Constitutional Orders

, 2018
O'Loughlin, E.A.
openalex   +2 more sources