Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Economic policy making and the role of special interest groups: Some evidence for South Korea [PDF]
It is now generally recognized that special interest group influence on economic decision making is not in theory a phenomenon restricted to democratic capitalism.
Dee, Philippa S.
core
Redesigning Rules for Participation in Local Governance
Corporatist arrangements in local governance are formal structures designed to incorporate interest groups in decision-making. Local corporatism is often dysfunctional. This may be a result of malign intent.
Liz Richardson, Francesca Gains
doaj +1 more source
Corporate Political Strategy on Three Continents A Managerial Comparative Approach at Global Level Part I - United States of America and Russia [PDF]
This is the second part of our study1 on corporate political activity, an issue that should be regarded as very important in the firm’s interaction with the political factor.
Simona BUŞOI, Amedeo ISTOCESCU
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Do Interest Groups Compete? [PDF]
This paper conducts a test of the hypothesis that interest groups compete strategically for influence with a policy-making agency. It adapts econometric methodology from the empirical industrial organization literature that was designed to work with ...
Ando, Amy
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Political Economy Reasons for Government Inertia: The Role of Interest Groups in the Case of Access to Medicines [PDF]
The reluctant reaction of western governments to the AIDS crisis in developing countries is only one example for policy areas where we observe a lack of political action despite a public interest in policy change.
Börner, Kira
core
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Providing Insights into the Challenges of Implementing Activity-Based Therapy in Canada: A Comparative Analysis Using Focus Group Interviews with Key Interest Groups. [PDF]
Kaiser A +9 more
europepmc +1 more source

