Results 151 to 160 of about 9,379,501 (285)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Overview of Undergraduate Oncology Interest Groups: Medical Students' Insights from a National Collaborative Network. [PDF]
J Cancer Educ, 2021 Rallis KS, Wang YA.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Informational Effects of Competition and Collusion in Legislative Politics [PDF]
We use a mechanism design approach to study the organization of interest groups in an informational model of lobbying. Interest groups influence the legislature only by communicating private information on their preferences and not by means of monetary ...
Martimort, David, Semenov, Aggey
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Hydraulic Bureaucracies and the Hydraulic Mission: Flows of Water, Flows of Power
Water Alternatives, 2009 Anchored in 19th century scientism and an ideology of the domination of nature, inspired by colonial hydraulic feats, and fuelled by technological improvements in high dam constructions and power generation and transmission, large-scale water resources ...
François Molle +2 more
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Interest Groups, Think Tanks, and Health Care Policy (1960s-Present) [PDF]
, 2014 Giaimo, Susan
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Sustainability: Science, Practice, & Policy, 2012 Sustainable buildings have often been niche products, but in recent years a new approach has emerged in Denmark aimed at mainstreaming and normalizing this mode of construction and seeking to attract ordinary Danes through market conditions.
Jesper Ole Jensen +3 more
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