Results 111 to 120 of about 4,256,481 (288)

Bureaucratic institutions and interests in the making of China's social policy [PDF]

open access: yes, 2003
Explanations of China’s post-Mao social policy have concentrated on the political, social, fiscal, and economic goals of the state and its governing elite.
Duckett, J.
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The Cash Rate and the Consumer: A Modern Australian Socio-Politico-Economic Saga

open access: yes, 2013
Griffith Business SchoolFull ...
Worthington, Andrew Charles   +1 more
core  

Influence of the Russian-American Relations on Kazakhstan at the Present Stage

open access: yesУправленческое консультирование, 2018
In the article various aspects of influence of the Russian-American relations on Kazakhstan at the present stage are considered. Special attention is paid to the Kazakh vector of the American policy and the relation of Russia.
R. Yu. Rybkin
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Protecting local Government Public Health Policy from vested interests

open access: yes, 2018
Background and challenges to implementation Article 5.3 of the Framework Convention on Tobacco Control states that “in setting and implementing public health policies with respect to tobacco control, parties shall act to protect these policies ...
Hilary Wareing   +2 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Trade-union movement in kazakhstan: problems and prospects

open access: yesХабаршы. Психология және социология сериясы, 2016
The main function of the trade-union organizations is consolidation of interests of workers and protection of their interests before the employer. The history of development of trade unions shows how difficult it is to satisfy needs of workers in the ...
Zh. Nurbekova   +2 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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