Results 121 to 130 of about 3,854,105 (316)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Financial competing interests were associated with favorable conclusions and greater author productivity in nonsystematic reviews of neuraminidase inhibitors

open access: yes, 2016
Objective: To characterize the conclusions and production of nonsystematic reviews about neuraminidase inhibitors relative to financial competing interests held by the authors.
Arachi, Diana   +6 more
core   +1 more source

Tourist Accommodation Choices in Nature-Based Destinations: The Case of Geotourism Destination Kras/Carso

open access: yesTourism and Hospitality
This paper explores the relationship between accommodation choices and visitor interests, and characteristics in the emerging cross-border Karst Geopark, a geologically rich nature-based destination.
Dejan Paliska, Gorazd Sedmak
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Common interests of humankind and the international regulation of the use of the force

open access: yes, 2018
The chapter discusses the philosophical foundations of the current regulation of the use of force. The chapter argues that, in correspondence with the emergence of a sphere of substantive rules protecting common interests of humankind, international ...
vincenzo cannizzaro
core  

The fog of integration: Reassessing the role of economic interests in European integration [PDF]

open access: yes, 2007
The main theories of European economic integration argue that private economic interests play an important role in the integration process. This role is a positive one, whereby economic interests provide the impetus and pressures for integration to move ...
Patrick Leblond, Leblond, Patrick.
core  

Survey of public interest in cycling during the Covid-19 pandemic

open access: yesSriwijaya Journal of Sport
The purpose of this research is to see the number of people's interest in cycling. Survey and interview methods were conducted to obtain research data. Respondents taken are people who do cycling at Taman Bunga Sumenep with a total of 25 respondents. The
Ipnu Ibrahim   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Teaching Topic Preferences in the Nature–Human–Society Subject: How Trainee Teachers Justify Their Likes and Dislikes

open access: yesEducation Sciences
This study focuses on the description and explanation of trainee teachers’ attitudes in specific educational situations. More precisely, it demonstrates the reasons why they prefer to teach certain Nature–Human–Society topics over others and, conversely,
Angelika Pahl, Reinhard Tschiesner
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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