Results 61 to 70 of about 1,902,719 (318)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Reminder Objects in the Connected Home of the Future and Beyond
Technologies, 2017 This paper presents best practices on how to design reminder objects. Reminder objects are digitally augmented everyday objects that break down and communicate complex information via sensory input and output.
Martina Uhlig, Henrik Rieß, Peter Klein
doaj +1 more source
Journal of Electrical Bioimpedance, 2023 Ultrasound guided peripheral nerve block (USgPNB) refers to anaesthetic techniques to deposit local anesthetic next to nerves, permitting painful surgery without necessitating general anesthesia.
Whelton Edel +8 more
doaj +1 more source
Natural‐language processing applied to an ITS interface [PDF]
, 1994 The aim of this paper is to show that with a subset of a natural language, simple systems running on PCs can be developed that can nevertheless be an effective tool for interfacing purposes in the building of an Intelligent Tutoring System (ITS).
Antonio Gisolfi +3 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Nature Communications, 2016 Given the scarcity and cost of platinum, it is important to develop sustainable processes for its recycling. Here, the authors report the dissolution of metallic platinum using reductive and oxidative gases to repetitively change its surface oxidation ...
Nejc Hodnik +8 more
doaj +1 more source
A multi-level interface model for damaged masonry [PDF]
, 2013 The aim of the present work is to propose a new micro-mechanical model in the context of the deductive approach used to derive interface models. This model, based on a previous study introduced previously by A. Rekik and F.
E. Sacco +7 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Evaluating the effects of fluid interface components on tabletop collaboration
, 2015 Tabletop displays provide exciting opportunities to support individual and collaborative activities such as planning, organizing, and storyboarding. It has been previously suggested that continuous flow of interface items can ease information access and ...
Hinrichs, Uta +2 more
core +1 more source