Results 51 to 60 of about 2,592,637 (335)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Boundary integral formulation for interfacial cracks in thermodiffusive bimaterials
, 2015 An original boundary integral formulation is proposed for the problem of a semi-infinite crack at the interface between two dissimilar elastic materials in the presence of heat flows and mass diffusion.
Morini, L., Piccolroaz, A.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
NUMERICAL SIMULATION OF DYNAMIC CRACK GROWTH OF BIMATERIAL INTERFACE CRACKS
Jixie qiangdu, 2021 Based on the extended finite element method（ XFEM）,the dynamic propagation behaviors of interface cracks and sub interface cracks in bimaterials are studied. A dynamic growth analysis model of bimaterial plate with interface crack and sub interface crack
ZHAO LuChun, ZHANG ZiWei, LI DingHe
doaj
Open Ceramics, 2023 Alumina-calcium hexaluminate refractories experience crack development under severe conditions, leading to a significant reduction in mechanical strength.
Guanglin Dong +9 more
doaj +1 more source
Study of three-dimensional crack fronts under plane stress using a phase field model
, 2010 The shape of a crack front propagating through a thin sample is studied using a phase field model. The model is shown to have a well defined sharp interface limit.
Henry, Hervé
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Effect of Pre-Strain on Crack Growth Behavior of Zr702/TA2/Q345R Composite Plate
Metals, 2022 The influence of pre-strain on the fatigue crack growth behavior of Zr702/TA2/Q345R composite plate is studied by experiments and the finite element method.
Binbin Zhou +6 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source