Results 41 to 50 of about 178,578 (290)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Understanding crack versus cavitation in pressure-sensitive adhesives: the role of kinetics

open access: yes, 2006
We perform traction experiments on viscous liquids highly confined between parallel plates, a geometry known as the probe-tack test in the adhesion community.
Fabre, P.   +3 more
core   +4 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

New developments in the application of configurational mechanics to crack propagation [PDF]

open access: yes, 2019
The numerical description of discrete cracks and their propagation remains one of the main difficulties in the modeling of quasi-brittle materials such as rock or concrete.
Carol, Ignacio   +2 more
core   +3 more sources

The compliance approach for analyzing biomaterial interface cracks

open access: yesComputer Assisted Methods in Engineering and Science, 2023
A numerical method is presented for analyzing the mixed mode interface crack between two dissimilar isotropic materials. A simple and efficient solution procedure is developed based on the finite element method and the compliance approach in conjunction
Hisham Abdel-Fattah, Sameer A. Hamoush
doaj  

Influence of matrix toughness and interfacial strength on the toughness of epoxy composites with ductile steel fabric reinforcement [PDF]

open access: yes, 2015
In the last decades, several studies have been performed on polymers reinforced with steel cords or wires. However, the diameter of these steel reinforcements was still quite large (200 micron and more).
Degrieck, Joris   +3 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Dynamics and ordering of weakly Brownian particles in directional drying [PDF]

open access: yes, 2017
Drying of particle suspensions is an ubiquitous phenomenon with many natural and practical applications. In particular, in unidirectional drying, the evaporation of the solvent induces flows which accumulate particles at the liquid/air interface.
Deville, Sylvain   +4 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Research on the fracture behavior of PBX under static tension

open access: yesDefence Technology, 2014
The fracture behavior of polymer-bonded explosive (PBX) seriously affects the safety and reliability of weapon system. The effects of interface debonding and initial meso-damage on the fracture behavior of PBX under quasi-static tension are studied using
Hu Guo   +3 more
doaj   +1 more source

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