Results 51 to 60 of about 178,578 (290)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A multi-level interface model for damaged masonry [PDF]

open access: yes, 2013
The aim of the present work is to propose a new micro-mechanical model in the context of the deductive approach used to derive interface models. This model, based on a previous study introduced previously by A. Rekik and F.
Lebon, Frédéric   +3 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Flexural Performance of Underground Combined Walls

open access: yesBuildings
Connecting diaphragm walls as permanent components of underground spaces in relation to basement sidewalls is an effective method for enhancing structural stability, reducing structural footprint, and improving waterproofing performance.
Chunchao Chen, Shihai Chen
doaj   +1 more source

Research on dynamic mechanical behavior and damage evolution mechanism of Cu/WCp laminated composites

open access: yesMaterials Research Express, 2021
In this paper, the effect of WCp particle content (3 and 15 vol.%) and laminate orientation on the mechanical behavior of laminated Cu/WCp/15p and Cu/WCp/3p composites under dynamic impact was investigated using the split Hopkinson pressure bar (SHPB ...
Zhang Yubo   +4 more
doaj   +1 more source

Effect of Original Layer Thicknesses on the Interface Bonding and Mechanical Properties of Ti-Al Laminate Composites [PDF]

open access: yes, 2016
It is of great significance in high-temperature aeroengine applications for large-surface-area TiAl laminate composites to be fabricated into Ti-Al3Ti parts by plastic forming and subsequent vacuum hot pressing.
Ali   +21 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Analysis of Crack Propagation in Composite Materials Using Mixed Finite Elements

open access: yesSelected Scientific Papers: Journal of Civil Engineering
This study investigates the application of fracture mechanics to analyze cracked structures, particularly focusing on cracks along interfaces in multilayer materials. Assuming perfectly plastic elastic behavior, small displacements, and plane structures,
Bougueroua Ahmed, Bouzerd Hamoudi
doaj   +1 more source

Enhancement of fatigue resistance by recrystallization and grain growth to eliminate bonding interfaces in Cu–Cu joints

open access: yesScientific Reports, 2022
Cu–Cu joints have been adopted for ultra-high density of packaging for high-end devices. However, cracks may form and propagate along the bonding interfaces during fatigue tests.
Jia-Juen Ong   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Home - About - Disclaimer - Privacy