Results 81 to 90 of about 178,578 (290)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Yantu gongcheng xuebaoThe interface cracking between the rammed earth supplement and the original site body, after construction, is a common issue for the reinforcement of the erosion area at the base of rammed earth sites.
CUI Kai 1, 2 , XU Pengfei 1, 2, YU Xiangpeng 1, 2, SHAO Hui'an 1, 2, WEI Xin 1, 2
doaj +1 more source
An aging evaluation of the bearing performances of glass fiber composite laminate in salt spray fog environment [PDF]
, 2019 The aim of the present paper is to assess the bearing performance evolution of pinned, glass-composite laminates due to environmental aging in salt-spray fog tests.
Bruzzaniti P. G. +4 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Influence of engineered interfaces on residual stresses and mechanical response in metal matrix composites [PDF]
Because of the inherent coefficient of thermal expansion (CTE) mismatch between fiber and matrix within metal and intermetallic matrix composite systems, high residual stresses can develop under various thermal loading conditions.
Arnold, Steven M., Wilt, Thomas E.
core +1 more source
Recent Milestones in Unraveling the Full-Field Structure of Dynamic Shear Cracks and Fault Ruptures in Real-Time: From Photoelasticity to Ultrahigh-Speed Digital Image Correlation [PDF]
, 2020 The last few decades have seen great achievements in dynamic fracture mechanics. Yet, it was not possible to experimentally quantify the full-field behavior of dynamic fractures, until very recently.
Lapusta, N., Rosakis, A. J., Rubino, V.
core
A symplectic analytical singular element for steady-state thermal conduction with singularities in composite structures [PDF]
, 2016 In modern design of composite structures, multiple materials with different properties are bound together. Accurate prediction of the strength of the interface between different materials, especially with the existence of cracks under thermal loading, is
Gao, H. Y. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Annealing tests of in-pile irradiated oxide coated U–Mo/Al–Si dispersed nuclear fuel [PDF]
, 2014 Authors do acknowledge the MERARG team for their experimental work (CEA) and F. Charollais, J. Noirot and finally B. Kapusta for their advices and comments.
BARRALLIER, Laurent +8 more
core +5 more sources