Results 61 to 70 of about 116,720 (306)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Characterizing the microstructural transition at the gray matter-white matter interface: Implementation and demonstration of age-associated differences

NeuroImage
Background: The cortical gray matter-white matter interface (GWI) is a natural transition zone where the composition of brain tissue abruptly changes and is a location for pathologic change in brain disorders.
Joan Y Song, Roman Fleysher, Kenny Ye, Mimi Kim, Molly E Zimmerman, Richard B Lipton, Michael L Lipton   +6 more
doaj   +1 more source

Focusing characteristics of a 4 πparabolic mirror light-matter interface

Journal of the European Optical Society-Rapid Publications, 2017
Background Focusing with a 4 π parabolic mirror allows for concentrating light from nearly the complete solid angle, whereas focusing with a single microscope objective limits the angle cone used for focusing to half solid angle at maximum.
Lucas Alber, Martin Fischer, Marianne Bader, Klaus Mantel, Markus Sondermann, Gerd Leuchs   +5 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Subsecond optically controlled domain switching in freestanding ferroelectric BaTiO3 membrane

Nature Communications
The quest to develop energy-efficient and fast optoelectronic control of memory devices is essential. In this respect, ferroelectric materials are gaining tremendous importance in information and communication technology.
Subhajit Pal, Lan-Tien Hsu, Haoying Sun, Sheng-Han Teng, Vivek Dwij, Emanuele Palladino, Yuefeng Nie, Samuel John, S. S. Prabhu, Anna Grünebohm, Joe Briscoe   +10 more
doaj   +1 more source

Propagating interfaces in mixtures of active and passive Brownian particles

New Journal of Physics, 2016
The emergent collective dynamics in phase-separated mixtures of isometric active and passive Brownian particles is studied numerically in two-dimensions. A novel steady-state of well-defined propagating interfaces is observed, where the interface between
Adam Wysocki, Roland G Winkler, Gerhard Gompper   +2 more
doaj   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

The role of surface-active macromolecules in the ice-nucleating ability of lignin, Snomax, and agricultural soil extracts [PDF]

Atmospheric Chemistry and Physics
Organic matter in agricultural soil dust can enhance dust's ice-nucleating ability relative to mineral dust and thus impact local cloud formation. But how is this organic matter able to nucleate ice?
K. A. Alden, K. A. Alden, K. A. Alden, P. Bieber, A. J. Miller, N. Link, B. J. Murray, N. Borduas-Dedekind   +7 more
doaj   +1 more source

Snowmass White Paper: Light Dark Matter Direct Detection at the Interface With Condensed Matter Physics [PDF]

, 2022
Andrea Mitridate, Tanner Trickle, Zhengkang Zhang, Kathryn M. Zurek   +3 more
openalex   +1 more source