Results 71 to 80 of about 68,576 (248)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Ultra‐Improved Interfacial Strength Between Metallic Surface and Polyurethane via Cost‐Effective Anodizing Process

Advanced Materials Interfaces
Interfacial strength at the metal‐adhesive joint is a pivotal parameter to define adhesive bond reliability and its overall mechanical performance. This study systematically investigates and optimizes sulfuric acid anodizing (SAA) parameters to promote ...
Umut Bakhbergen, Sherif Araby, Zhandos Tauanov, Nursultan Turdakyn, Reza Montazami, Fethi Abbassi, Gulnur Kalimuldina   +6 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Kinetics of Reverse Micelles Extraction of Nickel from Electroplating Wastewater Using Dinonylnaphthalene Sulfonic Acid

工程科学与技术, 2014
:The kinetics of Ni (Ⅱ) extraction by dinonylnaphthalene sulfonic acid (DNNSA) in kerosene from wastewater was investigated using a Lewis Cell. The different parameters affecting the extraction rate such as stirring speed, interfacial area，DNNSA ...
余静, 邱海浪, 夏雪, 江洪龙, 汪嘉杨, 叶芝祥, 杨迎春, 张雪乔   +7 more
doaj  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Local two-group bubble size model for adiabatic air–water flow in a large diameter pipe using CFD code

Case Studies in Thermal Engineering
Accurate prediction of bubble behavior in large diameter pipes is crucial for evaluating the performance of safety systems, steam generators, and heat exchangers in nuclear systems.
Jinyeong Bak, Manh Long Doan, Seongbae Park, Jae Jun Jeong, Byongjo Yun   +4 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Modification of SAC0307/Cu solder joints by FeCoNiCrCu particles: microstructure, comprehensive properties and aging reliability

Journal of Materials Research and Technology
The effects of adding varying amounts of FeCoNiCrCu particles on the microstructure, interfacial reaction, wettability, shear strength, and isothermal aging reliability of SAC0307/Cu solder joints were systematically investigated.
Lei Sun, Jing Wang, Peng He, Liang Zhang, Jing Li, Ruihong Song   +5 more
doaj   +1 more source