Results 61 to 70 of about 9,585,943 (278)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Enhanced interfacial strength of carbon fiber/PEEK composites using a facile approach via PEI&ZIF-67 synergistic modification

Journal of Materials Research and Technology, 2019
As a kind of metal-organic frameworks (MOFs) which possess large specific surface area and excellent thermal stability, zeolitic imidazolate framework-67 (ZIF-67) shows great application potentials because it can be synthesized in aqueous solutions at ...
Hansong Liu, Yan Zhao, Na Li, Xiaoran Zhao, Xiao Han, Shuang Li, Wenkuo Lu, Kai Wang, Shanyi Du   +8 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Effect of Folded Structures on Interfacial Solar-Driven Seawater Desalination

Membranes
Currently, solar-driven interface evaporation for seawater desalination is believed to be an effective way to overcome freshwater shortage. To improve the efficiency of solar-driven interfacial evaporators, designing the evaporator’s structure is ...
Shufang Zhu, Yuke Niu, Xu Yan
doaj   +1 more source

Enhancement of the in-plane and pin-load bearing behavior of a quasi-isotropic carbon fiber/epoxy matrix multi-scale laminate by modifying the fiber-matrix interphase using graphene nanoplatelets

Journal of Materials Research and Technology, 2020
The present work examines the effect of incorporating two different concentrations, 0.1% and 0.25%, of silane-functionalized graphene nanoplatelets GnP-GPTMS onto the carbon fiber surface of a quasi-isotropic laminate with the aim to enhance both, the ...
Abad Arcos-Alomía, Pascual Bartolo-Pérez, Alex Valadez-González, Pedro Jesus Herrera-Franco   +3 more
doaj   +1 more source

Mechanistic Modeling of Interfacial Area Transport in Large Diameter Pipes

, 2012
Flow in large pipes is important in a wide variety of applications. In the nuclear industry in particular, understanding of flow in large diameter pipes is essential in predicting the behavior of reactor systems.
Ishii, M., Hibiki, T., Schlegel, Joshua P., Smith, T. R.   +3 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Synergistic enhancement of film-substrate bonding strength in cemented carbide cutting tools with combined microtextures and TiAlN/TiN composite coatings

Results in Engineering
Although WCCo cemented carbide cutting tools exhibit high hardness, wear resistance and thermal stability, local stress concentration, interfacial damage accumulation, and localized delamination are prone to occur at the film-substrate interface of ...
Youzheng Cui, Minli Zheng, Yujia Xia, Changzhe Liu, Hui Jiang, Baoyi Bai, Zhongran Huang   +6 more
doaj   +1 more source

Use of an internal loop airlift bioreactor to produce polyhydroxyalkanoates by Stenotrophomonas rhizophila [PDF]

Chemical Industry and Chemical Engineering Quarterly
Airlift-type bioreactors present advantages over conventional systems such as efficient mass transfer, simplicity of construction, and low energy consumption.
Clifton-García Berenice, Villafaña-Rojas Juan, González-Reynoso Orfil, Robledo-Ortiz Jorge Ramon, Manríquez-González Ricardo, Gutiérrez-González Porfirio, González-García Yolanda   +6 more
doaj   +1 more source