Results 81 to 90 of about 277,260 (269)

Intermolecular Repulsion through Interfacial Attraction: Toward Engineering of Polymorphs [PDF]

Journal of the American Chemical Society, 2009
Understanding the formation of crystalline polymorphs is of importance for various applications of materials science. Polymorphism of Schiff base derivatives has recently attracted considerable attention because of its influence on photochromic and thermochromic properties of their 3D crystals. The present investigation extends the study of Schiff base
Kudernac T., Saendig N., Landaluce T. F., van Wees B. J., Rudolf P., Katsonis N., ZERBETTO, FRANCESCO, Feringa B. L.   +7 more
openaire   +4 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Band Structure Engineering of Interfacial Semiconductors Based on Atomically Thin Lead Iodide Crystals

, 2019
To explore new constituents in two-dimensional materials and to combine their best in van der Waals heterostructures, are in great demand as being unique platform to discover new physical phenomena and to design novel functionalities in interface-based ...
Cao, Yi, Cheng, Yang, Huang, Wei, Huang, Zhen, Li, Hai, Liu, Bowen, Liu, Jinqiu, Liu, Kaihui, Liu, Yue, Sun, Yan, Wang, Jianpu, Wang, Lin, Wang, Xiaoyong, Wang, Xinran, Wu, Jiangbin, Xie, Hongguang, Yu, Maotao, Yu, Peng, Zhou, Jian, Zhou, Liujiang, Zhou, Zishu, Zhu, Chao, Zhu, Wei   +22 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Measuring wheel/rail contact stresses using ultrasound [PDF]

, 2004
The investigation of contact area and pressure distribution in a wheel/rail contact is essential information required in fatigue and wear calculations to determine design life, regrinding requirements, and maintenance schedules.
Bjorklund, S., Dwyer-Joyce, R.S., Lewis, R., Marhsall, M.B., Olofsson, O.   +4 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Reconfigurable ferromagnetic liquid droplets. [PDF]

, 2019
Solid ferromagnetic materials are rigid in shape and cannot be reconfigured. Ferrofluids, although reconfigurable, are paramagnetic at room temperature and lose their magnetization when the applied magnetic field is removed.
Ashby, Paul D, Ceballos, Alejandro, Chai, Yu, Fischer, Peter, Forth, Joe, Hellman, Frances, Helms, Brett A, Jiang, Yufeng, Kent, Noah, Kim, Paul Y, Liu, Xubo, Russell, Thomas P, Shi, Shaowei, Streubel, Robert, Wang, Dong   +14 more
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Enhanced Luminescence and Thermal Stability in High Gd³⁺/Eu³⁺ Co-Doped Ba₃Y₄O₉ Phosphors via Co-Precipitation Method

Molecules
The co-precipitation method was successfully used to synthesize Ba3(Y0.6−xGd0.4Eux)4O9 (0.01 ≤ x ≤ 0.09) phosphors with heavy Gd3+ doping, resulting in significantly enhanced thermal stability and luminescence performance.
Dong Zhu, Chunfeng Wang, Xiaohuai Wang, Shun Han, Yuxiang Zeng, Ming Fang, Wenjun Liu, Deliang Zhu, Peijiang Cao, Youming Lu   +9 more
doaj   +1 more source