Results 51 to 60 of about 117,830 (308)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A two-dimensional model for extensional motion of a pre-stressed incompressible elastic layer near cut-of frequencies

open access: yes, 2001
A two-dimensional model for extensional motion of a pre-stressed incompressible elastic layer near its cut-off frequencies is derived. Leading-order solutions for displacement and pressure are obtained in terms of the long wave amplitude by direct ...
Pichugin, AV, Rogerson, GA
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Determination Of Interfacial Properties Between Metal Film And Ceramic Substrate With An Adhesive Layer

open access: yes, 2009
Peel test measurements and inverse analysis to determine the interfacial mechanical parameters for the metal film/ceramic system are performed, considering that there exist an epoxy interface layer between film and ceramic.
Zhao HF, Chen M, Jin Y, 赵海峰
core   +1 more source

Rare Earth Silicate Formation: A Route Towards High-k for the 22 nm Node and Beyond

open access: yesJournal of Telecommunications and Information Technology, 2023
Over the last decade there has been a significant amount of research dedicated to finding a suitable high-k/metal gate stack to replace conventional SiON/poly-Si electrodes. Materials innovations and dedicated engineering work has enabled the transition
Ivona Z. Mitrovic , Stephen Hall
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Reversible Loss of Bernal Stacking during the Deformation of Few-Layer Graphene in Nanocomposites

open access: yes, 2013
The deformation of nanocomposites containing graphene flakes with different numbers of layers has been investigated with the use of Raman spectroscopy. It has been found that there is a shift of the 2D band to lower wavenumber and that the rate of band ...
Novoselov, Kostya S.   +26 more
core   +1 more source

Improvement of interfacial strength and fatigue stability of aramid fiber/rubber composites by constructing multiscale interphase structures

open access: yesJournal of Materials Research and Technology
In this paper, employing nanomechanical scrutiny of aramid fibers and rubber, novel interfacial layers of different thicknesses were designed between aramid fibers and rubber using polymerizable deep eutectic solvents.
Hui Xu   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Ultrathin ZnS and ZnO Interfacial Passivation Layers for Atomic-Layer-Deposited HfO2 Films on InP Substrates

open access: yes, 2016
Ultrathin ZnS and ZnO films grown by atomic layer deposition (ALD) were employed as interfacial passivation layers (IPLs) for HfO2 films on InP substrates.
So Yeong Joo (2902630)   +4 more
core   +1 more source

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