Results 11 to 20 of about 491,602 (238)
Revista Mexicana de Oftalmología, 2016 Presentamos el caso de un ex toxicómano de 50 años que acudió a consulta de oftalmología con visión borrosa bilateral. En la anamnesis refería su desintoxicación 20 años atrás, con abstinencia total desde entonces y buena reinserción social.
Lucía Echevarría Lucas +5 more
doaj +2 more sources
Empleo del interferón contra el cáncer de piel
Columna MédicaIntroducción: El cáncer de piel es una neoplasia frecuente a nivel mundial. El interferón es una sustancia natural que ayuda al sistema inmunitario a combatir enfermedades como esta, su uso terapéutico, ha sido evaluado en un gran número de ...
Karla Hernández Acosta +3 more
doaj +2 more sources
Autoanticuerpos en pacientes hematológicos tratados con interferón alfa
Revista Cubana de Hematología, Inmunología y HemoterapiaSe estudió la presencia de autoanticuerpos en 45 pacientes con enfermedades hematológicas: 32 con leucemia mieloide crónica (LMC) y 13 con otras enfermedades linfoproliferativas (ELP).
Antonio A Bencomo Hernández +5 more
doaj +1 more source
VacciMonitor, 2009 Se estableció y validó un ELISA para la cuantificación del Interferón alfa 2b humano recombinante en el Ingrediente Farmacéutico Activo, definiéndose los criterios de validez del ensayo y basado en el cumplimiento de las Buenas Prácticas de Laboratorio ...
Susset Valderrama +6 more
doaj +1 more source
, 2023 El principal objetivo del estudio es identificar los miARN asociados al uso del interferón beta especialmente en la esclerosis múltiple. A partir de 8 muestras femeninas y 8 muestras masculinas se tomaron 2 grupos de estudio, uno de control y el otro de ...
Salazar Andrade, Andrea Cristina
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source