Results 71 to 80 of about 3,507,722 (308)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

The stability region of the two-user interference channel [PDF]

Information Theory Workshop, 2013
The stable throughput region of the two-user interference channel is investigated here. First, the stability region for the general case is characterized.
N. Pappas, M. Kountouris, A. Ephremides
semanticscholar   +1 more source

Bargaining Over the Interference Channel

2006 IEEE International Symposium on Information Theory, 2006
In this paper we analyze the interference channel as a conflict situation. This viewpoint implies that certain points in the rate region are unreasonable to one of the players. Therefore these points cannot be considered achievable based on game theoretic considerations.
Amir Leshem, Ephraim Zehavi
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Robust Transceiver Design for Correlated MIMO Interference Channels in the Presence of CSI Errors under General Power Constraints

Mathematics
In this paper, we consider a new design problem of optimizing a linear transceiver for correlated multiple-input multiple-output (MIMO) interference channels in the presence of channel state information (CSI) errors, which is a more realistic and ...
Jae-Mo Kang, Dong-Woo Lim
doaj   +1 more source

Transceiver Design Based on Nonlinear Precoding in MIMO Interference Channel [PDF]

Jisuanji gongcheng, 2018
Aiming at the co-channel interference between transceivers and data streams in Multi-Input Multiple-Output(MIMO) interference channel,a joint nonlinear Tomlinson-Harashima Precoding(THP) transceiver design method is proposed to minimize the total Mean ...
WANG Wei,XU Lingze,ZHOU Yuning,PAN Peng
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Multi-channel allocation algorithm for wireless Mesh network in coal mine emergency rescue

Gong-kuang zidonghua, 2015
For a problem that existing multi-channel allocation algorithms for wireless Mesh network were unable to resolve channel allocation jitter caused by transmission interference in coal mine emergency rescue, a multi-channel allocation algorithm was ...
ZHANG Liya, MENG Qingyong, WEN Liang
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source