Results 61 to 70 of about 1,542,926 (247)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Location-Based Mode Selection and Resource Allocation for Device-to-Device Underlay Communication

open access: yesDianxin kexue, 2014
Device-to-device(D2D)communication underlaying cellular networks can bring great benefits to spectrum resource utilization and users' throughput. However, because of the interference caused by D2D communication, interference cancellation and coordination
Jun Yao, Qing Huang
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Frequency Interference Analysis and Calculation of Geostationary-Orbit Satellite Network

open access: yes天地一体化信息网络, 2021
The status of the submission and coordination of the global geostationary-orbit (GSO) satellite networks, GSO satellites in orbit were reviewed.The international rules of interference analysis and calculation between GSO satellite networks, two ...
Chang LIU, Wenkang WEI, Wei LI
doaj   +2 more sources

Interference Coordination Using Precoding Schemes for Indoor Hotspots [PDF]

open access: yes, 2017
This paper investigates an interference coordination method for indoor hotspot deployment which includes cooperative communication between access points.
Nugraha, Toha Ardi
core  

User-centric intercell interference coordination in small cell networks

open access: yes, 2014
Small cell networks provide an effective way to meet the explosive growth of mobile data traffic, which, however, complicates the network structure and makes intercell interference management more challenging.
Jun Zhang   +5 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Goal-Oriented Interference Coordination in 6G In-Factory Subnetworks [PDF]

open access: yes
Subnetworks are expected to enhance wireless pervasiveness for critical applications such as wireless control of plants, however, they are interference-limited due to their extreme density. This paper proposes a goal-oriented joint power and multiple sub-
Artemenko, Alexander   +4 more
core   +1 more source

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