Results 91 to 100 of about 1,856,502 (376)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Measurement of Dielectric Suppression of Bremsstrahlung

, 1995
In 1953, Ter-Mikaelian predicted that the bremsstrahlung of low energy photons in a medium is suppressed because of interactions between the produced photon and the electrons in the medium. This suppression occurs because the emission takes place over on
A. B. Migdal, F. R. Arutyunyan, G. Niemi, H. A. Bethe, J. D. Jackson, J. L. White, L. A. Kelley, L. D. Landau, L. P. Keller, L. S. Rochester, M. Cavalli-Sforza, M. Cavalli-Sforza, M. L. Perl, M. L. Ter-Mikaelian, P. Anthony, P. E. Bosted, P. L. Anthony, R. Becker-Szendy, R. Becker-Szendy, S. R. Klein, S. R. Klein, T. Stanev, V. M. Galitsky   +22 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Full-Duplex Systems Using Multi-Reconfigurable Antennas

, 2014
Full-duplex systems are expected to achieve 100% rate improvement over half-duplex systems if the self-interference signal can be significantly mitigated. In this paper, we propose the first full-duplex system utilizing Multi-Reconfigurable Antenna (MRA)
Ahmed, Elsayed, Cetiner, Bedri A., Eltawil, Ahmed M., Li, Zhouyuan   +3 more
core   +1 more source

Electronic transmission in Graphene suppressed by interlayer interference [PDF]

AIP Advances, 2013
We investigate electronic transport property of a graphene monolayer covered by a graphene nanoribbon. We demonstrate that electronic transmission of a monolayer can be reduced when covered by a nanoribbon. The energy at which the transmission reduction occurs depends on the width of nanoribbon.
Feng Zhai, Jian Wu, Jun-Qiang Lu, Yongjin Jiang, Daniel Valencia, Feng Liu   +5 more
openaire   +5 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Side Lobe Suppression in NC-OFDM Systems Using Variable Cancellation Basis Function

IEEE Access, 2017
In non-continuous orthogonal frequency division multiplexing (NC-OFDM)-based cognitive radio system, the sidelobe suppression methods use the fixed length rectangular windowing functions for canceling carriers (CCs) like the extended active interference ...
Shaik Yasmin Fathima, Muhammad Zia Ur Rahman, K. Murali Krishna, Shakira Bhanu, Mirza Shafi Shahsavar   +4 more
doaj   +1 more source

Suppression of tunneling by interference in half-integer--spin particles

, 1992
Within a wide class of ferromagnetic and antiferromagnetic systems, quantum tunneling of magnetization direction is spin-parity dependent: it vanishes for magnetic particles with half-integer spin, but is allowed for integer spin.
A. J. Leggett, A. Messiah, B. Barbara, C. Paulsen, D. D. Awschalom, D. Loss, D. Loss, Daniel Loss, David P. DiVincenzo, E. Fradkin, E. M. Chudnovsky, E. Manousakis, F. D. M. Haldane, F. D. M. Haldane, G. Grinstein, J. Klauder, J. L. Van Hemmen, J. L. Van Hemmen, M. V. Berry, P. C. E. Stamp, R. Rajaraman   +20 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

A study on electromagnetic interference analysis and suppression method for traction system of high-speed EMU

机车电传动, 2022
According to the complexity of electromagnetic interference of traction system of high-speed EMU, and in combination with the design of the vehicle system, the EMI coupling paths of traction system were analyzed.
YANG Deyong, ZHU Bingquan, CHEN Ying, ZHI Yongjian, YUAN Keliang, YAN Guanglin   +5 more
doaj