Results 141 to 150 of about 443,905 (332)

Radar and Communication Spectral Coexistence on Moving Platform with Interference Suppression [PDF]

open access: gold, 2022
Junhui Qian   +5 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

An experimental SMI adaptive antenna array for weak interfering signals [PDF]

open access: yes
A modified sample matrix inversion (SMI) algorithm designed to increase the suppression of weak interference is implemented on an existing experimental array system.
Dilsavor, R. L., Gupta, I. J.
core   +1 more source

Stable suppression of tumorigenicity by virus-mediated RNA interference [PDF]

open access: bronze, 2002
Thijn R. Brummelkamp   +2 more
openalex   +1 more source

Multi-Interference Suppression Network: Joint Waveform and Filter Design for Radar Interference Suppression

open access: yesElectronics
With the advancement of electromagnetic interference and counter-interference technology, complex and unpredictable interference signals greatly reduce radar detection, tracking, and recognition performance. In multi-interference environments, the overlap of interference cross-correlation peaks can mask target signals, weakening radar interference ...
Rui Cai, Chenge Shi, Wei Dong, Ming Bai
openaire   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

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