Results 61 to 70 of about 436,144 (334)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Suppression of co-channel interference in NGSO constellation system with interference alignment

open access: yesTongxin xuebao, 2021
Aiming at the problem that in the current space, non-geostationary satellite orbit (NGSO) constellation systems were increasing day by day, there are more and more satellite networks nearby orbiting using the same frequency band, and the problem of co ...
Bing DU   +5 more
doaj   +2 more sources

Magnetic field dependence of valley splitting in realistic Si/SiGe quantum wells

open access: yes, 2006
The authors investigate the magnetic field dependence of the energy splitting between low-lying valley states for electrons in a Si/SiGe quantum well tilted with respect to the crystallographic axis.
Coppersmith, S. N.   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Interocular suppression prevents interference in a flanker task [PDF]

open access: yesFrontiers in Psychology, 2015
Executive control of attention refers to processes that detect and resolve conflict among competing thoughts and actions. Despite the high-level nature of this faculty, the role of awareness in executive control of attention is not well understood. In this study, we used interocular suppression to mask the flankers in an arrow flanker task, in which ...
Melissa-Ann Mackie   +7 more
openaire   +4 more sources

Indoor Massive MIMO Deployments for Uniformly High Wireless Capacity

open access: yes, 2017
Providing consistently high wireless capacity is becoming increasingly important to support the applications required by future digital enterprises. In this paper, we propose Eigen-direction-aware ZF (EDA-ZF) with partial coordination among base stations
Baracca, Paolo   +5 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Review of Synthetic Aperture Radar Interference Suppression

open access: yesLeida xuebao, 2020
Synthetic Aperture Radar (SAR) has attracted much attention in the recent decades owing to its allweather and high-resolution working mode. As an active radar system, the high-resolution imaging process of SAR systems is affected by different types of ...
HUANG Yan   +4 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

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