Results 81 to 90 of about 448,902 (332)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Review of Synthetic Aperture Radar Interference Suppression

Leida xuebao, 2020
Synthetic Aperture Radar (SAR) has attracted much attention in the recent decades owing to its allweather and high-resolution working mode. As an active radar system, the high-resolution imaging process of SAR systems is affected by different types of ...
HUANG Yan, ZHAO Bo, TAO Mingliang, CHEN Zhanye, HONG Wei   +4 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Enhancement and suppression of spontaneous emission and light scattering by quantum degeneracy

, 2000
Quantum degeneracy modifies light scattering and spontaneous emission. For fermions, Pauli blocking leads to a suppression of both processes. In contrast, in a weakly interacting Bose-Einstein condensate, we find spontaneous emission to be enhanced ...
A. Görlitz, A. P. Chikkatur, A. P. Chikkatur, B. DeMarco, B. DeMarco, C. C. Bradley, D. G. Fried, D. M. Stamper-Kurn, D. M. Stamper-Kurn, D. Pines, E. Timmermans, G. Ferrari, J. Ruostekoski, K. B. Davis, K. Helmerson, K. Huang, M. H. Anderson, M. J. Holland, N. N. Bogoliubov, R. H. Dicke, T. Busch, W. Ketterle   +21 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Suppression of Biodynamic Interference by Adaptive Filtering [PDF]

, 1984
Preliminary experimental results obtained in moving base simulator tests are presented. Both for pursuit and compensatory tracking tasks, a strong deterioration in tracking performance due to biodynamic interference is found.
Grunwald, A. J., Merhav, S. J., Velger, M.   +2 more
core   +1 more source

Suppression of tunneling by interference in half-integer--spin particles

, 1992
Within a wide class of ferromagnetic and antiferromagnetic systems, quantum tunneling of magnetization direction is spin-parity dependent: it vanishes for magnetic particles with half-integer spin, but is allowed for integer spin.
A. J. Leggett, A. Messiah, B. Barbara, C. Paulsen, D. D. Awschalom, D. Loss, D. Loss, Daniel Loss, David P. DiVincenzo, E. Fradkin, E. M. Chudnovsky, E. Manousakis, F. D. M. Haldane, F. D. M. Haldane, G. Grinstein, J. Klauder, J. L. Van Hemmen, J. L. Van Hemmen, M. V. Berry, P. C. E. Stamp, R. Rajaraman   +20 more
core   +1 more source

Projection Versus Prewhitening for EEG Interference Suppression [PDF]

IEEE Transactions on Biomedical Engineering, 2012
Suppression of strong, spatially correlated background interference is a challenge associated with electroencephalography (EEG) source localization problems. The most common way of dealing with such interference is through the use of a prewhitening transformation based on an estimate of the covariance of the interference plus noise.
Shun Chi, Wu, A Lee, Swindlehurst, Po T, Wang, Zoran, Nenadic   +3 more
openaire   +2 more sources

Interference Suppression in EEG Dipole Source Localization through Reduced-Rank Beamforming [PDF]

, 2023
Jimenez-Cruz Eduardo, David Gutiérrez
openalex   +1 more source